Stephen L Archer Selected Research

Phenylephrine (Neo-Synephrine)

10/2020	Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
1/2019	Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
9/2002	O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.

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Stephen L Archer Research Topics

Disease

43	Pulmonary Arterial Hypertension 12/2023 - 10/2003
26	Pulmonary Hypertension 01/2024 - 01/2002
25	Hypoxia (Hypoxemia) 01/2023 - 06/2002
15	Neoplasms (Cancer) 01/2023 - 06/2005
11	Vascular Diseases (Vascular Disease) 01/2022 - 01/2010
10	Inflammation (Inflammations) 04/2024 - 10/2012
10	Vascular Remodeling 10/2020 - 12/2006
8	Ischemia 01/2024 - 03/2004
8	Heart Failure 01/2023 - 03/2004
8	Hypertrophy 01/2022 - 06/2005
8	Fibrosis (Cirrhosis) 01/2022 - 04/2015
6	Right Ventricular Hypertrophy 03/2013 - 10/2007
4	Pneumonia (Pneumonitis) 04/2024 - 12/2013
4	Reperfusion Injury 01/2024 - 01/2014
4	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 08/2003
4	Right Ventricular Dysfunction 01/2022 - 04/2013
4	Lung Diseases (Lung Disease) 01/2019 - 10/2005
3	Heart Arrest (Cardiac Arrest) 01/2024 - 02/2015
3	Connective Tissue Diseases (Connective Tissue Disease) 12/2023 - 02/2010
3	Coronary Artery Disease (Coronary Atherosclerosis) 10/2023 - 12/2016
3	Microvascular Rarefaction 10/2020 - 10/2013
3	Major Depressive Disorder (Major Depressive Disorders) 07/2004 - 08/2003
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2024 - 01/2014
2	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2023 - 11/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 10/2010
2	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2020
2	Necrosis 01/2020 - 02/2015
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2020 - 02/2015
2	Cardiogenic Shock 01/2020 - 12/2016
2	Atrial Fibrillation 01/2019 - 02/2009
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2017 - 12/2016
2	Familial Primary Pulmonary Hypertension 01/2016 - 11/2010
2	Thrombosis (Thrombus) 10/2012 - 01/2003
2	Patent Ductus Arteriosus 02/2008 - 09/2004
2	Hypotension (Low Blood Pressure) 01/2005 - 03/2004
2	Coronary Disease (Coronary Heart Disease) 01/2005 - 12/2003
2	Erectile Dysfunction 09/2004 - 01/2002
1	Myocardial Infarction 01/2024
1	Hematologic Diseases (Blood Diseases) 10/2023
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2023
1	Fetal Hypoxia 01/2023
1	Infections 12/2022

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2024 - 05/2012
15	MonocrotalineIBA 10/2023 - 04/2007
13	Oxygen (Dioxygen)IBA 01/2023 - 09/2004
12	Dynamins (Dynamin)IBA 01/2024 - 05/2012
8	CalciumIBA 01/2024 - 12/2006
7	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 01/2023 - 01/2007
7	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 01/2007
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2011 - 01/2003
5	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 11/2020 - 06/2005
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 06/2006
4	Pyruvate KinaseIBA 01/2023 - 12/2017
4	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 03/2013
4	Vasodilator Agents (Vasodilators)IBA 01/2020 - 11/2010
4	superoxide dismutase 2IBA 01/2016 - 06/2010
4	Transcription Factors (Transcription Factor)IBA 01/2013 - 02/2008
4	Sildenafil Citrate (Viagra)FDA Link 05/2011 - 10/2003
3	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 10/2013
3	Semaxinib (SU5416)IBA 01/2022 - 03/2012
3	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2018
3	EnzymesIBA 01/2021 - 01/2016
3	Ion Channels (Ion Channel)IBA 01/2021 - 01/2016
3	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 10/2020 - 09/2002
3	RotenoneIBA 01/2019 - 06/2002
3	CreatinineIBA 01/2019 - 05/2008
3	PotassiumIBA 01/2016 - 07/2007
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2014 - 10/2005
3	SurvivinIBA 01/2013 - 06/2005
3	Epoprostenol (Prostacyclin)FDA LinkGeneric 10/2012 - 11/2010
2	mitochondrial calcium uniporterIBA 01/2023 - 02/2017
2	GTP Phosphohydrolases (GTPases)IBA 01/2023 - 01/2020
2	pro-brain natriuretic peptide (1-76)IBA 10/2020 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 10/2020 - 09/2018
2	CollagenIBA 01/2020 - 01/2018
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2020 - 01/2019
2	Pyruvic Acid (Pyruvate)IBA 01/2020 - 03/2013
2	Carbon MonoxideIBA 01/2019 - 02/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2018
2	riociguatIBA 01/2018 - 07/2013
2	rho-Associated KinasesIBA 01/2017 - 04/2007
2	Adrenergic Agents (Adrenergic Drugs)IBA 06/2014 - 12/2012
2	GadoliniumIBA 02/2012 - 11/2011
2	Phosphodiesterase 5 InhibitorsIBA 11/2009 - 07/2007
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 07/2007 - 07/2006
2	Potassium Channels (Potassium Channel)IBA 07/2007 - 01/2002
2	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 06/2006 - 01/2002
2	NitratesIBA 01/2005 - 03/2004
2	Paroxetine (Paxil)FDA LinkGeneric 12/2003 - 08/2003
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 04/2024
1	7-(N-(3-aminopropyl)amino)heptan-2-oneIBA 12/2023
1	DNA Methyltransferase 3AIBA 12/2023
1	Digoxin (Digitek)FDA LinkGeneric 01/2023

Therapy/Procedure

26	Therapeutics 01/2024 - 12/2004
3	Anesthesia 02/2006 - 12/2004
2	Heterologous Transplantation (Xenotransplantation) 01/2021 - 05/2012
2	Resuscitation 01/2020 - 02/2015
2	Cardiopulmonary Resuscitation (CPR) 01/2020 - 02/2015
2	Drug Therapy (Chemotherapy) 08/2010 - 09/2004
1	Heart Transplantation (Grafting, Heart) 01/2024